7.65%
improvement in net elasticity
1 hour
Cutometer R5, n=32; p=0.015.
SeneGenceReview6-Week Independent Anti-Aging Study
NeoTight® Rejuvenating Anti-Wrinkle Serum
One application. A measurable gain in elasticity.
Within one hour, independent instrumental testing measured a significant improvement in net elasticity, while expert grading separately documented firmer-looking skin. By Week 6, expert line grades and participant feedback supported improved-looking lines and more youthful-looking skin.
33 completed1-hour + 6-week resultsInstrument + expert grading
24.53%
improvement in crow’s-feet appearance
Week 6
Expert-graded mean change, n=31; no p-value reported.
96.88%
said the product hydrated skin well
Week 6
Participant perception, n=32.
Clinical results at a glance
See the product results in one view.
Compare the product, timing, and measured result in the diagrams below.
SeneGenceReviewClinical Results
Immediate + progressive performance
A rapid elasticity result, followed by visible and perceived improvement.
Measured after one application
Cutometer R5 net elasticity improved 7.65% one hour after application (n=32; p=0.015). In a separate expert assessment, firmer-looking skin improved 12.05% at the same visit (n=31; descriptive mean change).
Crow’s-feet appearance24.53%
Week 6 expert-graded mean improvement, n=31; no p-value reported.
Upper-lip line appearance13.64%
Week 6 expert-graded mean improvement, n=31; no p-value reported.
Nasolabial-fold appearance7.14%
Week 6 expert-graded mean improvement, n=31; no p-value reported.
87.50%said overall skin appearance improved.
84.38%said fine lines and wrinkles looked reduced.
78.13%saw reduced crow’s-feet appearance.
71.88%noticed a firmer-looking, lifted appearance after application.
Consumer perception
Week 6 questionnaire results are self-reported agreement among 32 respondents and are shown separately from instrument and expert assessments.
SeneGenceReviewClinical Results
Technical study record
A signed final source supports a precise one-hour elasticity result and complementary six-week wrinkle-appearance results.
Independent laboratoryValidated Claim Support, LLC
Tested productNeoTight Rejuvenating Anti-Wrinkle Serum
Design6-week single-arm baseline comparison
Population34 enrolled; 33 completed; ages 48-69
Use2-3 pumps, twice daily
EvidenceCutometer, Visioscan, expert grading, photography, questionnaire
Source date13 November 2020
Instrumental context
| Assessment | Baseline | Follow-up | Source-reported mean % improvement | p-value |
|---|---|---|---|---|
| Cutometer R5 net elasticity | 0.5023 | 0.5407 at 1 hour | +7.65% | 0.015 |
| Cutometer R0 firmness | 0.2966 | 0.3326 at 1 hour | -12.12% (unfavorable) | 0.011 |
| Visioscan crow’s-feet SEw | 185.89 | 166.23 at Week 6 | -10.57% | 0.278 |
| Visioscan nasolabial-fold SEw | 206.78 | 174.54 at Week 6 | -15.59% | 0.156 |
For R5, increase indicates improvement; for R0 and SEw, decrease indicates improvement. The statistically significant R5 net-elasticity response at 1 hour is the primary instrumental result; additional endpoints are included for complete study context.
Study application
Expert-graded appearance and participant-perception results are presented separately from the instrument findings. Results apply to NeoTight Rejuvenating Anti-Wrinkle Serum under the reported six-week study design.
SeneGenceReviewTechnical Evidence
Independent laboratory evidence
Original source pages follow.
View the complete source record.
The selected VCS laboratory source pages follow.
The complete PDF pairs this consumer summary with the selected independent laboratory source pages.
Open complete laboratory report (PDF)LaboratoryValidated Claim Support, LLC
Source date13 November 2020
Independent laboratory source pages are included in the complete PDF. Participant-identifying information has been removed where indicated; aggregate findings are unchanged.
Want that firmer-looking finish in your routine? See what NeoTight® Rejuvenating Anti-Wrinkle Serum does, where it goes and how to choose it, or return to all clinical results.
Accessible source-page companion
PDF page 19 is an image facsimile. This companion presents a manually checked aggregate table with the reported baseline and 1-hour values, signed changes, p-values, t-values, and R0/R5 associations.
Administrative report identifiers and participant-level rows are omitted here. The unchanged signed source PDF remains available above.
PDF page 19 — One-hour Cutometer firmness and elasticity aggregate
Source date: November 13, 2020. Source page: 21 of 28.
This companion presents the aggregate average and statistical-analysis rows; participant-level rows are omitted.
| Statistic | Baseline | 1 hour | % improvement | |||
|---|---|---|---|---|---|---|
| R0 (firmness) | R5 (elasticity) | R0 (firmness) | R5 (elasticity) | R0 (firmness) | R5 (elasticity) | |
| Average | 0.2966 | 0.5023 | 0.3326 | 0.5407 | -12.12% | 7.65% |
| p | — | — | 0.011* | 0.015* | ||
| t | — | — | 2.702 | 2.562 | ||
* Statistically significant: p<0.050 statistically significant; p>0.050 not statistically significant.
The source labels the R0 change as -12.12% improvement and the R5 change as 7.65% improvement. The negative R0 sign is preserved.