clinical finding

SenePlex+ Evening Moisturizer Normal to Dry — surface-renewal study

in the study

SenePlex+® Evening Moisturizer Normal to Dry

what it showed

Visible surface-cell turnover progressed from 49% greater at day 13 to 80% at day 16, 94% at day 17, and up to 100% greater by day 18; mean full visible turnover was 15.5 days versus 18.0 days for untreated skin.

In the 20-day study, visible surface-cell turnover increased progressively and reached up to 100% greater turnover than untreated skin by Day 18.

The measured change supports a fresher, smoother-looking skin surface over the study period.

updated 2026-08-24 · clinical finding

Visible surface-cell turnover timepoints. Bars show 49 percent at day 13, 80 percent at day 16, 94 percent at day 17, and up to 100 percent at day 18 for the treated Evening Moisturizer formula site versus untreated control.

Complete measurements and study notes

6 details

How it was evaluated: Dansyl-chloride visual scoring of treated and untreated sites on the same subjects
Who took part: 34 enrolled; 33 completed
Statistical context: Significant versus control on days 2–18; headline and mean-time comparisons p<0.001
Information checked: 2026-08-03

Measured results · 20-day study; day-13 endpoint

Surface-cell turnover

49% greater

The treated SenePlex+ formula site showed 49% greater visible surface-cell turnover than the untreated control site at day 13.

What was measured: visible surface-cell turnover
When it was measured: 20-day study; day-13 endpoint

Measured results · 20-day study; day-16 endpoint

Surface-cell turnover

80% greater

The treated SenePlex+ formula site showed 80% greater visible surface-cell turnover than the untreated control site at day 16.

What was measured: visible surface-cell turnover
When it was measured: 20-day study; day-16 endpoint

Measured results · 20-day study; day-17 endpoint

Surface-cell turnover

94% greater

The treated SenePlex+ formula site showed 94% greater visible surface-cell turnover than the untreated control site at day 17.

What was measured: visible surface-cell turnover
When it was measured: 20-day study; day-17 endpoint

Measured results · 20-day study; day-18 endpoint

Surface-cell turnover

up to 100% greater

In an independent 20-day study, Evening Moisturizer Normal to Dry with SenePlex+® showed up to 100% greater visible surface-cell turnover than untreated skin by day 18.

What was measured: visible surface-cell turnover
When it was measured: 20-day study; day-18 endpoint

Mean residual dansyl-chloride surface-stain intensity

0.00 treated vs 0.18 untreated

At day 18, mean residual surface-stain intensity was 0.00 at the treated site versus 0.18 at the untreated control site; lower values indicate faster clearance.

When it was measured: 20-day study; day-18 endpoint

Measured results · 20-day study

Mean time to full visible surface turnover

15.5 ± 0.4 days treated vs 18.0 ± 0.4 days control

Mean time to full visible surface turnover was 15.5 ± 0.4 days at the treated site versus 18.0 ± 0.4 days at the untreated control site.

When it was measured: 20-day study