What are plant exosomes and secretomes in skincare?
Quick answer
Plant exosomes are a kind of vesicle: tiny membrane-bound particles that plant cells release. A secretome is the wider set of everything a cell releases. In SeneGence skincare, plant exosomes appear as Centella Asiatica Leaf Vesicles in GLP Complex™ with SenePlex+® and Exosomes, beside Ornithine HCl, Phospholipids, Glycolipids and Caprooyl Tetrapeptide-3. In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks and 23.4% at eight weeks, and improved the look of facial volume by 8.4% at eight weeks. See the GLP Complex study.
By SeneGence · 
Alan Kante, publisher · Updated
- 4 min read
How do exosomes, secretomes and orchid stem cells differ?
| Term | What it is | At SeneGence today | Explore |
|---|---|---|---|
| Plant exosomes | Membrane-bound vesicles that plant cells release; exosomes are one subtype of vesicle. | Centella Asiatica Leaf Vesicles in GLP Complex™ with SenePlex+® and Exosomes. | The GLP Complex formula |
| Secretomes | The wider set of substances a cell releases. | Our blend of clinically proven peptides, exosomes, and proprietary SenePlex+® stem cell technology (secretomes), paired with skin-nourishing botanicals, delivers visible results without unnecessary additives. Beauty Book 2026 (p. 8). The orchid of Mount Yasur inspired SenePlex+®, and its legend keeps growing. Today, orchid stem cell secretomes help visibly lift and improve the appearance of sagging skin in SeneCell™ SenePlex+® StemCell Concentrate and NeoTight™ Eye Serum, and more secretomes are coming from the same orchid legend. Beauty Book 2026 (pp. 15, 19). | Beauty Book 2026 · Joni’s founder story |
| Orchid stem cells and extracts | Calanthe Discolor (Ebine) Extract, the orchid stem cells in SenePlex+®, which also carries Orchis Mascula (Orchid) Flower Extract. | Part of today’s SenePlex+® complex. | The SenePlex+® ingredients |
What do the vesicles in GLP Complex bring?
Centella Asiatica plant-derived exosomes help skin communication for a smoother, stronger-looking appearance, with collagen support, brightening and a reduced look of hyperpigmentation. Beauty Book 2026 (p. 9). GLP Complex™ with SenePlex+® and Exosomes visibly restores lost facial volume and luminosity, smooths the look of deep wrinkles and supports firmer, more supple, radiant skin. The serum uses Ornithine HCl, Phospholipids, and Glycolipids for the look of facial volume, with Centella Asiatica Leaf Vesicles, Caprooyl Tetrapeptide-3 with Dextran, and SenePlex+® completing the formula. Review the complete GLP Complex formula. In an independent clinical study of 31 men and women ages 38–75 using GLP Complex™ with SenePlex+® and Exosomes, 100% showed visible improvement in deep wrinkles and 81% showed visible improvement in facial volume after eight weeks, assessed by expert clinical analysis compared with baseline. See the GLP Complex formula. Beauty Book 2026 (p. 15). For the full study, see whether plant-derived exosomes work in skincare or the GLP Complex study. GLP Complex is for deep lines and the look of lost facial volume; see how to use it or GLP Complex.
What orchid care does SeneGence use today?
Today’s orchid care lives in SenePlex+®, which carries two orchids. Its orchid stem cells, Calanthe Discolor (Ebine) Extract, are chosen to help improve the look of sagging, drooping skin for a firmer, more lifted appearance, and Orchis Mascula (Orchid) Flower Extract is its second orchid. Beauty Book 2026 (p. 9). Meet the orchid stem cells in SenePlex+®.
The orchid of Mount Yasur inspired SenePlex+®, and its legend keeps growing. Today, orchid stem cell secretomes help visibly lift and improve the appearance of sagging skin in SeneCell™ SenePlex+® StemCell Concentrate and NeoTight™ Eye Serum, and more secretomes are coming from the same orchid legend. Beauty Book 2026 (pp. 15, 19). Explore SenePlex+ and its origin. Read the orchid legend.
What are the orchid stem cell secretomes in SenePlex+®?
Our blend of clinically proven peptides, exosomes, and proprietary SenePlex+® stem cell technology (secretomes), paired with skin-nourishing botanicals, delivers visible results without unnecessary additives. Beauty Book 2026 (p. 8).
A secretome is what cells release. Calanthe discolor orchid stem cells are the source of the orchid stem cell secretomes in SenePlex+®.
Study results at a glance
GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study5 results
| Result | Kind of result | When it was measured |
|---|---|---|
| In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks. | Measured result | 4 weeks |
| All 31 participants showed image-analyzed improvement in deep-wrinkle appearance after four and eight weeks of using GLP Complex™ with SenePlex+® and Exosomes. | Measured result | 4 and 8 weeks |
| In an independent study, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 23.4% at eight weeks. | Measured result | 8 weeks |
| In an independent study, GLP Complex™ with SenePlex+® and Exosomes improved the look of facial volume by 8.4% at eight weeks. | Measured result | 8 weeks |
| At eight weeks, 81% of participants showed image-analyzed improvement in the look of facial volume after using GLP Complex™ with SenePlex+® and Exosomes. | Measured result | 8 weeks |
See the full finding: GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study · Open the study PDF