Which SeneGence DayTime and Evening Moisturizers fit my skin?
Quick answer
Choose the SeneGence DayTime and Evening Moisturizer pair for your skin type, Dry, Normal to Dry or Normal to Oily, or the Microbiome pair for oily, sensitive skin: lightweight, makeup-ready care by day and richer overnight care by night. In a 20-day independent clinical study of 33 women ages 19–65, measured by expert clinical grading compared with baseline, Evening Moisturizer – Normal to Dry with SenePlex+® and orchid stem cells accelerated skin cell renewal by 35.7%. Beauty Book 2026 (p. 6).
By SeneGence · 
Alan Kante, publisher · Updated
- 4 min read
Which morning and night pair fits your skin?
| Your skin | Morning | Night | Explore |
|---|---|---|---|
| Dry | DayTime Moisturizer – Dry supports skin renewal and moisture retention with stem-cell and peptide care. Multi-weight Hyaluronic Acid supplies all-day hydration, while barrier care helps skin look smoother and plumper. | Evening Moisturizer – Dry supports the skin’s natural overnight repair cycle and helps minimize the appearance of pores. Stem-cell care and lipids smooth, replenish and restore skin overnight. | DayTime Moisturizer - Dry · Read the official ingredients and directions · Beauty Book 2026 |
| Normal to Dry | DayTime Moisturizer – Normal to Dry refines the look of tone and luminosity with peptides. Lightweight, all-day hydration and protection smooth skin for a flawless makeup base. | Evening Moisturizer – Normal to Dry helps boost ceramides to support the skin barrier. Essential fatty acids and vitamins support collagen and combat photoaging, while natural AHAs give a gentle, retinol-like smoothing benefit. | DayTime Moisturizer - Normal to Dry · Evening Moisturizer - Normal to Dry · Beauty Book 2026 |
| Normal to Oily | DayTime Moisturizer – Normal to Oily hydrates and helps balance moisture, mattifies a shiny T-zone and refines the look of enlarged pores, and its peptides refine the look of tone and luminosity. Epilobium Angustifolium (Willow Herb) Extract helps soothe and calm irritated skin, and a Bacillus Ferment from Spain’s Rio Tinto joins SenePlex+®. | Evening Moisturizer – Normal to Oily hydrates and helps balance moisture overnight, helps mattify a shiny T-zone and refine the look of enlarged pores, with Bacillus Ferment from Spain’s Rio Tinto and SenePlex+®. | DayTime Moisturizer - Normal to Oily · Evening Moisturizer - Normal to Oily · Beauty Book 2026 |
| Oily and sensitive | Microbiome Defense Daytime Moisturizer SPF 15 provides broad-spectrum UVA/UVB protection with Zinc Oxide and Octisalate. Antioxidants defend against blue light and environmental stressors, while probiotic care supports microbiome resilience and clearer-looking skin. | Microbiome Restorative Evening Moisturizer helps restore microbiome balance overnight. Deep hydration improves the look of tone and texture, while barrier support helps skin look calmer and clearer. | Microbiome Defense Daytime Moisturizer SPF 15 · Microbiome Restorative Evening Moisturizer · Beauty Book 2026 |
What do the DayTime and Evening Moisturizers share?
All three DayTime and all three Evening Moisturizers carry the same tone-care peptide pair. The ingredient manufacturer designed this two-peptide system, Palmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1, for more even-looking tone and lighter-looking dark spots. It also reports a 56-day study of the pair. Read the two-peptide research.
How do I choose within my skin type?
For dry skin, compare DayTime and Evening Moisturizer – Dry. For normal-to-dry skin, compare the Normal-to-Dry pair; used with its 3 in 1 Cleanser, that pair is the tested SenePlex+ regimen (see the regimen study). For normal-to-oily skin, the Normal to Oily pair keeps hydration light and oil-balancing; both carry a Bacillus Ferment from Spain’s Rio Tinto, one of the extremophile ingredients SeneGence uses. For oily, sensitive skin, the Microbiome pair brings sun protection by day. Microbiome Defense Daytime Moisturizer SPF 15 gives broad-spectrum UVA/UVB protection with Zinc Oxide 6% and Octisalate 5%. See its label. Apply Microbiome Defense Daytime Moisturizer SPF 15 generously and evenly as the last skincare step, 15 minutes before sun exposure, and reapply at least every 2 hours; use a water-resistant sunscreen if swimming or sweating.
Where do moisturizers go in my routine?
Moisturizer comes after cleansing, Climate Control and any treatment serums. By day, DayTime Moisturizer becomes the base for MakeSense® Original Foundation; by night, Evening Moisturizer is the last step unless you add Collagen Firming Night Pak over it. See the complete skincare order.