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product guide

SeneGence Microbiome Collection: Ferment Skin Care from Morning to Night

The Microbiome Collection gives each part of your skin-care day its own formula: a comfortable cleanse, a lightweight hydration step, a daytime moisturizer with SPF 15 and a richer moisturizer for night. Ferments run through all four, each with its own job.

The Microbiome Collection contains Microbiome Correcting Cleanser, Microbiome Boosting Serum, Microbiome Defense Daytime Moisturizer SPF 15, and Microbiome Restorative Evening Moisturizer.

updated 2026-09-28 · product guide

Product details

The four Microbiome formulas for morning and evening

SeneGence Microbiome Collection: Ferment-Led Day-to-Night Care

The Microbiome Collection contains Microbiome Correcting Cleanser, Microbiome Boosting Serum, Microbiome Defense Daytime Moisturizer SPF 15, and Microbiome Restorative Evening Moisturizer. There is more to a ferment than a drink of moisture. Lactobacillus Ferment conditions the surface so dry-looking skin feels supple; filtered yeast ferment helps a cosmetic hold on to water. Research on Streptococcus thermophilus explores support for skin’s own barrier lipids, while pomegranate ferment has a place in cosmetic science’s enzyme-led surface refining. Sphingomonas Ferment Extract adds a texture story, valued for the silky texture it can lend a formula.

Current context
use together as a daily skincare regimen

What comes in the current Microbiome SkinCare Regimen Set, and the serum sold separately

Microbiome SkinCare Regimen Set: The Current Four-Product Assortment

The Microbiome SkinCare Regimen Set brings together Microbiome Correcting Cleanser, Microbiome Defense Daytime Moisturizer SPF 15, Microbiome Restorative Evening Moisturizer and EyeCrème, with Microbiome Boosting Serum sold separately.

Current context
while the current US set contents remain unchanged
References and current sources

where it fits

what it means for you

Cleanse with Microbiome Correcting Cleanser, follow with Microbiome Boosting Serum morning and evening, then use Microbiome Defense Daytime Moisturizer SPF 15 by day or Microbiome Restorative Evening Moisturizer at night. The Microbiome SkinCare Regimen Set brings the cleanser, both moisturizers and EyeCrème together; Boosting Serum is sold separately. After cleansing, you can add Climate Control before the serum for extra preparation; its SenePlex+® yeast-and-kelp bioferment enzymes bring a gently renewed look to the surface.