What did SeneGence’s tested Normal-to-Dry skincare regimen improve?
SeneGence’s Normal-to-Dry cleansing and morning-and-evening moisturizing routine is for skin that wants a comfortable cleanse, lightweight daytime hydration and richer overnight moisture. In Validated Claim Support’s independent eight-week study, the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together improved Corneometer-measured hydration by 49.99% immediately after application in 32 participants and by 28.62% at eight weeks in 31 participants, compared with baseline.
By SeneGence · 
Alan Kante, publisher · Updated
When is Normal to Dry the right choice?
Choose Normal to Dry when skin wants moisture and softness without the weight of the richest Dry formulas. The creamy cleanser leaves skin soft and smooth, DayTime Moisturizer brings a lightweight, luminous finish, and Evening Moisturizer supplies richer overnight care.
If cleansing already feels comfortable but the richest layers keep leaving unwanted weight, compare Normal to Dry with the Dry routine. For the wider starting decision, choose your SeneGence Core 4.
What does the Normal-to-Dry cleanser add?
3 in 1 Cleanser - Normal to Dry combines cleansing, toning and exfoliating in a creamy wash that gently removes impurities and makeup while hydrating for soft, smooth-feeling skin.
Pyrus Malus (Apple) Fruit Extract brings the exfoliating role; Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract hydrates and conditions; Lycium Barbarum Fruit Extract supplies the goji-berry antioxidant role. Canarium Indicum (Nangai) Seed Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Persea Gratissima (Avocado) Oil and Simmondsia Chinensis (Jojoba) Seed Oil join the formula, along with Lactobacillus Ferment and Sodium Hyaluronate.
What makes the daytime moisturizer different?
DayTime Moisturizer - Normal to Dry brings an instant boost of hydration and a lightweight, luminous finish. Its care includes the appearance of pores, fine lines, wrinkles and visible signs of sun damage, together with a firmer, more lifted-looking complexion and moisture-barrier support.
Squalane softens and smooths; Polygonum Aviculare Extract is the knotgrass ingredient selected for the visible signs of photo-aging; Calanthe Discolor (Ebine) Extract supports a more contoured, lifted-looking appearance. Bis(Tripeptide-1) Copper Acetate contributes the ingredient-level firming and wrinkle-care role.
Palmitoyl sh-Octapeptide-24 Amide and Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 are the peptide pair in both current Normal-to-Dry moisturizers. Their maker describes the pair for more even-looking tone and lighter-looking dark spots. Explore the two-peptide tone-care pairing.
What makes the evening moisturizer worth returning to?
Evening Moisturizer - Normal to Dry is a rich, ultra-nourishing night cream with a lightweight feel. It helps refine skin texture, even the look of tone and diminish the appearance of lines while supporting moisture and a radiant morning complexion.
Carthamus Tinctorius (Safflower) Seed Oil, Canarium Indicum (Nangai) Seed Oil, Butyrospermum Parkii (Shea) Butter and Rosa Canina (Rose Hip) Seed Oil give the formula its nourishing oil-and-butter character. Niacinamide is the amide form of vitamin B3, studied in cosmetic science for smoother-looking skin and more even-looking tone; Garcinia Mangostana (Mangosteen) Fruit Extract contributes antioxidant care.
Calanthe Discolor (Ebine) Extract and Ganoderma Lucidum (Mushroom) Stem Extract support the youthful, lifted-looking appearance. Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76 is the plant-produced fusion peptide in this current formula. See the ingredient’s skin-appearance research, or compare the Normal-to-Dry day and night moisturizers.
How do you use the three products morning and evening?
In the morning and evening, gently massage 3 in 1 Cleanser - Normal to Dry onto moist face and neck. Rinse thoroughly and follow with the appropriate SeneGence DayTime or Evening Moisturizer.
In the morning after cleansing, use 1–2 pumps of DayTime Moisturizer - Normal to Dry and apply evenly to the face and neck daily.
In the evening after cleansing, apply a quarter-size amount of Evening Moisturizer - Normal to Dry to the face and neck daily. Gently massage it into the skin, then use your fingertips to press and roll.
How does the routine connect to aging intelligently?
SeneGence brings together senescence and intelligence: the process of aging intelligently. Here, the care follows your day—cleansing, lightweight morning moisture and richer evening moisture—with continued use at the heart of the eight-week research.
The three individual current Normal-to-Dry formulas carry SenePlex+®. This proprietary technology pairs biofermented Saccharomyces Cerevisiae (Yeast) Extract and Laminaria Digitata (Kelp) Extract for gentle-looking surface renewal with orchid stem cells, Calanthe Discolor (Ebine) Extract, in all three formulas, and Orchis Mascula (Orchid) Flower Extract in the cleanser and DayTime Moisturizer, for resilient-looking skin; prickly pear and humectants support hydration and comfort.
On Joni Rogers-Kante’s search for extremophile organisms in Vanuatu, the orchid of the Mount Yasur caldera inspired SenePlex+® and its renewal-minded approach. Follow the Vanuatu orchid story into SenePlex+®, or explore its ingredient roles.
What did the instruments measure beyond hydration?
In Validated Claim Support’s independent eight-week study of the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together, Cutometer R0 measurements improved firmness by 7.06% at week two and 6.59% at week eight compared with baseline, with 32 participants at each timepoint; a lower R0 reading indicates firmer skin.
Open SenePlex+ Clinical for the complete regimen findings and methods, or read the eight-week regimen evidence.
Which formulas did the study evaluate?
The study evaluated the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together. These findings describe that tested combination.
The product directions and ingredient teaching here describe the individually named US products; the clinical report identifies the formulas used in its study. Read the complete study.
What looked different after eight weeks?
In Validated Claim Support’s independent eight-week study of the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together, expert grading found a 23.60% mean improvement in visible radiance compared with baseline at week eight, and 96.88% of the 32 participants improved on that radiance endpoint.
At week eight in Validated Claim Support’s independent study of the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together, expert grading compared with baseline found improved visible firmness in 80.65% of 31 participants, improved texture or smoothness in 71.88% of 32 participants, improved tone evenness in 56.25% of 32 participants, and improved fine-line or wrinkle appearance in 31.25% of 32 participants.
How did the routine feel to the participants?
At week eight in Validated Claim Support’s independent study of the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together, all 32 questionnaire participants—100%—agreed that their skin felt more moisturized, 100% agreed that their skin tone looked more supple, and 100% agreed that skin texture felt smoother; these are consumer agreement results.
At week eight in Validated Claim Support’s independent study of the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer used together, 96.88% of the 32 questionnaire participants agreed that skin looked more luminous, radiant or bright, and 96.88% said they would buy the regimen.
Where does the day-18 surface-renewal result fit?
Tested Evening Moisturizer Normal to Dry showed up to 100% greater visible surface-cell turnover by day 18 versus untreated skin. Read the Evening Moisturizer surface-renewal study.
What comes in the current Normal-Dry SkinCare Regimen Set?
The Normal-Dry SkinCare Regimen Set brings together 3 in 1 Cleanser - Normal to Dry, DayTime Moisturizer - Normal to Dry, Evening Moisturizer - Normal to Dry and EyeCrème. The eight-week regimen study evaluated the cleanser and the two moisturizers used together. EyeCrème adds its own dedicated eye-area job to the four-product set.
For nourishing eye-area moisture and a brighter, smoother, more rested-looking finish, stipple a small amount of EyeCrème around the eye area with your ring finger, morning and evening, after cleansing and before moisturizer. Explore EyeCrème and its own eight-week findings.
Shop the Normal-Dry SkinCare Regimen Set on SeneGence, or choose the Normal-to-Dry cleanser, DayTime Moisturizer and Evening Moisturizer individually.
What is the complete Normal-to-Dry cleanser ingredient declaration?
Aqua/Water/Eau Cetyl Alcohol Glyceryl Stearate PEG-120 Methyl Glucose Dioleate Glycerin Sodium Cocoyl Isethionate Stearic Acid Pyrus Malus (Apple) Fruit Extract Palmitic Acid Canarium Indicum (Nangai) Seed Oil Limnanthes Alba (Meadowfoam) Seed Oil Persea Gratissima (Avocado) Oil Simmondsia Chinensis (Jojoba) Seed Oil Achillea Millefolium (Yarrow) Extract Camellia Sinensis (Green Tea) Leaf Extract Coffea Arabica (Coffee) Seed Extract Euterpe Oleracea Fruit Extract Garcinia Mangostana Fruit Extract Lycium Barbarum Fruit Extract Morinda Citrifolia Fruit Extract Punica Granatum Fruit Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Calanthe Discolor (Ebine) Extract Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Orchis Mascula (Orchid) Flower Extract Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Lactobacillus Ferment Sodium Hyaluronate Panthenol Tocopheryl Acetate Glycol Distearate Laureth-4 Butylene Glycol Acrylates Copolymer Xanthan Gum Coconut Acid Pentylene Glycol Ethylhexylglycerin Sclerotium Gum Lecithin Sodium Isethionate Pullulan Trisodium Ethylenediamine Disuccinate Lauric Acid Myristic Acid Silica Citric Acid Glucosamine HCl Urea Gluconolactone 1 2-Hexanediol Caprylyl Glycol Calcium Gluconate Potassium Sorbate Phenoxyethanol Sodium Benzoate Parfum/Fragrance Benzyl Alcohol Limonene. Synthetic
What is the complete Normal-to-Dry daytime moisturizer ingredient declaration?
Aqua/Water/Eau Glycerin C12-20 Acid PEG-8 Ester Caprylic/Capric Triglyceride Squalane Propanediol Cetearyl Alcohol Caprylic/Capric/Myristic/Stearic Triglyceride Palmitoyl Sh-Octapeptide-24 Amide Bis(Tripeptide-1) Copper Acetate Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 Sodium Hyaluronate Calanthe Discolor (Ebine) Extract Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Ganoderma Lucidum (Mushroom) Stem Extract Polygonum Aviculare Extract Camellia Sinensis (Green Tea) Leaf Extract Coffea Arabica (Coffee) Seed Extract Euterpe Oleracea Fruit Extract Garcinia Mangostana Fruit Extract Lycium Barbarum Fruit Extract Morinda Citrifolia Fruit Extract Punica Granatum Fruit Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Orchis Mascula (Orchid) Flower Extract Tocopheryl Acetate Tocopherol Panthenol Sclerocarya Birrea Seed Oil Phenoxyethanol Dimethicone Ceteareth-20 Carbomer Boron Nitride Potassium Sorbate Allantoin Ethylhexylglycerin Parfum/Fragrance Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Caprylyl Glycol 1 2-Hexanediol Citric Acid Xanthan Gum Gluconolactone Butylene Glycol Sodium Benzoate Urea Glucosamine HCL Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Calcium Gluconate Benzyl Benzoate Benzyl Alcohol Limonene. Synthetic
What is the complete Normal-to-Dry evening moisturizer ingredient declaration?
Aqua/Water/Eau Carthamus Tinctorius (Safflower) Seed Oil Canarium Indicum (Nangai) Seed Oil Glyceryl Stearate Butyrospermum Parkii (Shea) Butter Niacinamide Pentylene Glycol Cetearyl Alcohol Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters Rosa Canina (Rose Hip) Seed Oil Propanediol Glycerin Sodium Stearoyl Lactylate Butylene Glycol Behenyl Alcohol Sodium Stearoyl Glutamate Calanthe Discolor (Ebine) Extract Oryza Sativa (Rice) Bran Extract Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Ganoderma Lucidum (Mushroom) Stem Extract Helianthus Annuus (Sunflower) Extract Rosmarinus Officinalis (Rosemary) Leaf Extract Camellia Sinensis (Green Tea) Leaf Extract Coffea Arabica (Coffee) Seed Extract Euterpe Oleracea Fruit Extract Garcinia Mangostana (Mangosteen) Fruit Extract Lycium Barbarum (Goji) Fruit Extract Morinda Citrifolia (Noni) Fruit Extract Punica Granatum (Pomegranate) Fruit Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Palmitoyl Sh-Octapeptide-24 Amide Lactic Acid/Glycolic Acid Copolymer Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 Sodium Hyaluronate Tocopherol Panthenol Ethylhexylglycerin Polyacrylate Crosspolymer-6 Xanthan Gum Trisodium Ethylenediamine Disuccinate 1 2-Hexanediol Caprylyl Glycol Citric Acid Gluconolactone T-Butyl Alcohol Polyvinyl Alcohol Calcium Gluconate Urea Glucosamine HCl Phenoxyethanol Sodium Benzoate Parfum/Fragrance Benzyl Benzoate Benzyl Alcohol Limonene. Synthetic
Which three products were used together in the Normal-to-Dry regimen study?
The tested combination was Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer and Evening Moisturizer. The current set also includes EyeCrème for dedicated eye-area moisture.
Why use a different moisturizer in the morning and evening?
DayTime Moisturizer - Normal to Dry brings lightweight hydration and a luminous daytime finish. Evening Moisturizer - Normal to Dry brings richer overnight moisture and care for a radiant, more even-looking complexion.
Can I buy the Normal-to-Dry study components individually?
Yes. Choose 3 in 1 Cleanser - Normal to Dry, DayTime Moisturizer - Normal to Dry and Evening Moisturizer - Normal to Dry individually through their SeneGence product pages, or choose the Normal-Dry SkinCare Regimen Set for those three plus EyeCrème.
