clinical finding

Palmitoyl Tripeptide-1 — 29-day lip-care study

in the study

Manufacturer study of a Palmitoyl Tripeptide-1 lip-care material

what it showed

Sederma reports improved hydration, superficial wrinkles, average lip volume, smoothness, and flaking after 29 days.

You will also find Palmitoyl Tripeptide-1 in LipSense® Long-Lasting Lip Liner Pencil.

In LipSense® Long-Lasting Lip Liner Pencil, Palmitoyl Tripeptide-1 contributes lip hydration, smoothness, and fuller-looking-lip care.

updated 2026-09-19 · clinical finding

Complete measurements and study notes

2 details

How it was evaluated: Human instrumental measures, dermatologist assessment, and participant observation without a separate placebo
Who took part: 10 women ages 20–40 with thin, small, dry lips
Statistical context: Sederma reports changes in hydration, superficial lip wrinkles, average lip volume, smoothness, and flaking after 29 days.
Information checked: 2026-09-12

Measured results · day 29

Hydration, superficial wrinkles, and average lip volume

hydration 60% higher, superficial wrinkles 29% lower, and average lip volume 40.7% higher

For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, Sederma reports hydration 60% higher, superficial wrinkles 29% lower, and 40.7% higher average lip volume at day 29 in an uncontrolled 10-woman study of a colorless lipstick containing 1% material, used three times daily.

When it was measured: day 29

Lip condition, smoothness, and flaking

improved lip condition and smoothness with less flaking

For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, Sederma reports that the 10 participants noticed improved lip condition and smoothness with less flaking at day 29 after using the 1% material colorless lipstick three times daily.

When it was measured: day 29