clinical finding
in the study
Manufacturer studies of Caprooyl Tetrapeptide-3, including human serum studies of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material
what it showed
In a manufacturer’s randomized, placebo-controlled split-temple study in 27 women ages 40–65, a serum containing 2.5% of its Glycerin, Water, Dextran and Caprooyl Tetrapeptide-3 material produced a 16% average reduction in the appearance of fine lines and wrinkles at day 28, measured from silicone replicas after twice-daily application.
GLP Complex™ with SenePlex+® and Exosomes, SeneCell™ SenePlex+® StemCell Concentrate, and MakeSense® Silk Primer & Pore Minimizer contain Caprooyl Tetrapeptide-3 with Dextran, chosen for smoother-looking skin and softer-looking fine lines and wrinkles.
The shared peptide system connects GLP Complex™, SeneCell™, and MakeSense® Silk Primer & Pore Minimizer around smoother-looking lines and firmer-looking skin; choose among them by the serum, concentrate, or primer job you need.
16% average improvement
Atrium Innovations reports 16% average improvement in fine-line and wrinkle appearance at day 28 in a randomized split-temple serum study of Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3.
up to 29% improvement
In the same randomized split-temple serum study, Atrium Innovations reports that the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material improved fine-line and wrinkle appearance by up to 29% at day 28.
27% average and up to 35%
In the age-defined 50–65 subgroup of the same 27-woman randomized split-temple serum study of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material, Atrium Innovations reports 27% average and up to 35% improvement in fine-line and wrinkle appearance at day 56.
favorable perceptions of smoothness, firmness, evenness, and a rested look
In a separate 30-woman self-assessment of a serum with 2.5% of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material used twice daily, Atrium Innovations reports favorable perceptions of smoothness, firmness, evenness, and a rested look at day 56, plus favorable eye-area tolerability.
improvement versus placebo in 78% of participants
In a 27-woman split-temple ultrasound study of a serum with 2.5% of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material used twice daily, Atrium Innovations reports improvement versus placebo in 78% of participants on the upper-dermis entropy measure at day 168.
laminin 26% higher and fibronectin 60% higher
In an in vitro fibroblast assay of Caprooyl Tetrapeptide-3, Atrium Innovations reports laminin 26% higher and fibronectin 60% higher after 48 hours.
collagen VII staining 34% higher and laminin-5 staining 49% higher
In a corticoid-stressed four-donor human-skin explant model of Caprooyl Tetrapeptide-3, Atrium Innovations reports collagen VII staining 34% higher and laminin-5 staining 49% higher versus corticoid alone at day 3.
helped prevent the junction flattening seen with corticoid alone
In the corticoid-stressed four-donor human-skin explant model, Atrium Innovations reports that Caprooyl Tetrapeptide-3 helped prevent the dermal-epidermal-junction flattening seen with corticoid alone at day 3.
Caprooyl Tetrapeptide-3 has been studied with Dextran for smoother-looking lines and firmer-looking skin. You will find the pair in GLP Complex™, SeneCell™ and MakeSense® Silk Primer & Pore Minimizer.