Skip to content

clinical finding

Five sh-Oligopeptide and sh-Polypeptide factors in Advanced SenePlex+ Renewal Serum

in the study

Manufacturer study of sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, and sh-Polypeptide-11

what it showed

LABIO reports 21% improvement in crow’s-feet appearance at four weeks and a separate below-eye wrinkle measure improved 46% at four weeks.

Advanced SenePlex+® Renewal Serum with Retinol carries all five biotechnology-made peptides LABIO studied for softer-looking crow’s-feet and lines beneath the eyes, bringing that peptide combination into nighttime renewal care.

In Advanced SenePlex+® Renewal Serum with Retinol, the five-factor complex contributes smoothing and visible-renewal care.

Complete measurements and study notes

3 details
How it was evaluated
PRIMOS Lite 3D crow’s-feet measurement and a separate below-eye wrinkle image-analysis measure; public protocol is incomplete
Who took part
The public brochure does not disclose sample size, material concentration, comparator, or cadence
Statistical context
LABIO reports improvement in crow’s-feet and a separate below-eye wrinkle measure over four weeks.
Information checked
2026-09-12

Measured results · two weeks; four weeks

Crow’s-feet appearance

10% improvement at two weeks and 21% at four weeks

Using PRIMOS Lite 3D to measure crow’s-feet after use of a cosmetic formula containing sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, and sh-Polypeptide-11, LABIO reports appearance improvement of 10% at two weeks and 21% at four weeks.

When it was measured
two weeks; four weeks

Below-eye wrinkle measure

38% improvement at two weeks and 46% at four weeks

For the material containing sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, and sh-Polypeptide-11, LABIO reports a below-eye wrinkle image-analysis measure improved 38% at two weeks and 46% at four weeks.

When it was measured
two weeks; four weeks

Measured results

Five sh-Oligopeptide and sh-Polypeptide factors in Advanced SenePlex+ Renewal Serum

Advanced SenePlex+® Renewal Serum with Retinol contains sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9 and sh-Polypeptide-11. These biotechnology-made peptides have been studied together for softer-looking crow’s-feet and lines beneath the eyes.